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In La Disparition, which is the longest lipogram ever written (a lipogram being a piece of writing which deliberately does not use one or more letters), an eccentric man named Anton Vowl disappears, leaving his friends to solve the clues and puzzles he’s left behind. There’s a constant sense for them that there is something missing, not just a man but some facet of their universe, and as they realize what it is, horrible things begin to happen to them, one by one. It’s a deeply weird, fascinating read, whether in the original French or in any translation (since E is the most frequently used letter in French, each of the translations leaves out the most common letter in their own language).
Perec followed up La Disparition by writing Les Revenentes, which contains no vowels except E.
The Chaos Bitches 